Analgesic Effect of Aqueous Extract of Achillea Millefolium L. on Rat’s Formalin Test 1-*Mahdi Noureddini ,2- Vahid-reza Rasta
نویسنده
چکیده
Achillea millefolium L. (Asteraceae), popularly known as yarrow, has been used in traditional medicine to treat complaints such as gastrointestinal disturbances, hemorrhages, wounds, inflammation and pain. The aim of the present study was to assess the analgesic effects of aqueous extract of Achillea millefolium L. (AE) in the rat’s formalin test. Oral administration of different doses of AE (80, 160 and 320 mg/kg) induced a dose-dependent antinociception, both in the first and second phases of the formalin test. The results of the present study support the proposal that Achillea millefolium L. has analgesic effects. These findings justify the traditional use of the plant for treating pain and suggest that its activity may be resulted from its central action.
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